TwistedBrush Pro Studio - A powerful and unique natural media painting program.
Autodesk SketchBook - SketchBook drawing and painting software provides designers, architects, and concept artists the tools to sketch ideas quickly and create beautiful illustrations.
Corel Painter - Corel Painter is media painting software.
MediBang Paint - The official site for MediBang Paint, the free digital painting and manga creation software. You can download the latest version of MediBang Paint here, and get news and tutorials.
Krita - Krita is a professional FREE and open source painting program. It is made by artists that want to seaffordable art tools for everyone. Concept art. texture and matte painters, illustrations and comics.
Artrage - A simple but lovely natural media painting and sketching program.