Ruffle - An open source Flash player
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BlueMaxima's Flashpoint - the webgame preservation project.
Sencha Animator - I just learned about the halt to production and development of Sencha Animator.
CheerpX for Flash - its adobe flash player in webassembly
GSAP - GSAP (GreenSock Animation Platform) is a suite of JavaScript tools for high-performance animations that work in all major browsers.