Inkscape - Inkscape is a free, open source professional vector graphics editor for Windows, Mac OS X and Linux.
CrazyTalk Animator - CrazyTalk Animator, the next level of 2D animation. Create actors using any photo or illustration.
Blender - Blender is the open source, cross platform suite of tools for 3D creation.
Renderforest Video - Free animation and intro maker, slideshow and video creator
Cinema 4D - Cinema 4D is a 3D modeling, animation, motion graphics and rendering application.
Spine - Spine is 2D animation software designed specifically for software and game development.