FlexSim - Simulation software to model, simulate, predict, and visualize systems in manufacturing, material handling, healthcare, warehousing, mining, etc.
AnyLogic - AnyLogic has changed simulation modeling and expanded its application into complex business environments. The unmatched flexibility of multimethod modeling allows users to capture the complexity of virtually any system, at any level of detail.
ns-3 - a discrete-event network simulator for internet systems
Paessler Multi Server Simulator - Paessler Multi Server Simulator is inexpensive and robust software that helps you power massive-scale testing.
Simio - Facility design simulation & production scheduling
Mininet - Mininet is a robust and inexpensive Instant Virtual Network designed to function on standard PCs like Laptops and Desktops.