Recommended and mentioned products
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The easiest way to run Python, Spyder with SciPy and friends out of the box on any Windows PC...
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Nuitka is a Python compiler.
Try nuitka BTW I have used the mentioned here pyinstaller, pex … last time I needed to this, nuitka worked flawlessly and better than pyinstaller.
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Inno Setup is a free installer for Windows programs.
If you want an actual "installer", check out Inno Setup. It will take your WinPython or PyInstaller directory and install it like a real program, including creating shortcuts and all the rest if you want it to.