Home-Assistant.io - Home Assistant is an open-source home automation platform running on Python 3.
ioBroker - flexible and modular application for the IoT and Smarthome
Google Home - Set up, manage, and control your Chromecast, Chromecast Audio and Google Home devices.
openHAB - "empowering the smart home" - vendor and technology agnostic open source home automation
Jeedom - Jeedom is a complete home-automation software.
SEQUEmatic - SEQUEmatic lets you build sequences to link together your various smart devices.