Home-Assistant.io - Home Assistant is an open-source home automation platform running on Python 3.
ioBroker - flexible and modular application for the IoT and Smarthome
openHAB - "empowering the smart home" - vendor and technology agnostic open source home automation
Home - Securely control all your HomeKit accessories from your favorite iOS device.
Jeedom - Jeedom is a complete home-automation software.
Apple HomePod - The new home entertainment system by Apple