CherryPy - CherryPy allows developers to build web applications in much the same way they would build any other object-oriented Python program.
Django - The Web framework for perfectionists with deadlines
Flask - a microframework for Python based on Werkzeug, Jinja 2 and good intentions.
TurboGears - TurboGears is a web framework to create a database-driven, ready-to-extend application in minutes.
web2py - Web2py is an open source web application framework.
Tornado - A Python web framework and asynchronous networking library, originally developed at FriendFeed