Wiiji - Wiiji is the perfect joystick solution for Wii remotes on Mac.
JoyToKey - JoyToKey enables users to control the keyboard using any USB compatible controller (Dualshock 3, Xbox 360, etc.)
DarwiinRemote - SourceForge presents the DarwiinRemote project. DarwiinRemote is an open source application.
Xpadder - Xpadder simulates the keyboard and mouse using your gamepad What does Xpadder let you do?
Joystick 2 Mouse - Joystick 2 Mouse is a little utility which gives mouse usefulness to associated joysticks and joypads.
Keysticks - Control your PC using an Xbox controller instead of the mouse and keyboard