Kontakt - With KONTAKT 6, you can sound like a snare drum, a symphony orchestra, or anything in between, from a universe of sampled instruments.
MadMapper - The Mapping Software
UVI Falcon - Sampler/synth hybrid instrument
Resolume - Resolume is an application for live video performances.
Pianoteq - Pianoteq is a virtual piano that runs on your computer.
Linux Show Player - Sound player designed for stage productions