Tweetbot - Sync your timeline across your iPhone, iPad, and Mac. Mute tweets by user, hashtag, tweet source, or keywords (including regex). 3rd Party support for image, video, read later, and timeline sync services.
Gwibber - Gwibber is an open source microblogging client for GNOME developed with Python and GTK.
TweetDeck - TweetDeck is your personal browser for staying in touch with what’s happening now.
Choqok - Choqok - KDE Micro-Blogging Client The name comes from an ancient Persian word, means Sparrow!
HootSuite - Enhance your social media management with Hootsuite, the leading social media dashboard. Manage multiple networks and profiles and measure your campaign results.
Whalebird - Whalebird is a Mastodon client for desktop application.