PowerMill - PowerMill is an advanced CAM software that comes with a flexible way to get done with your complex high-speed and five-axis machining processing.
LinuxCNC (the Enhanced Machine Control) - LinuxCNC: an open source CNC machine controller. It can drive milling machines, lathes, 3d printers, laser cutters, plasma cutters, robot arms, hexapods, and more.
SolidCAM - The ‘Best-in-Class’ CAM Solution for Efficient & Profitable CNC-Programming Inside Your CAD
Mach3 - Mach3 is very popular among the Hobby CNC community.
Mastercam - Mastercam's Dynamic Milling is a game changer for us.
PyCAM - PyCAM is a toolpath generator for 3-axis CNC machining.