What are some alternatives?
When comparing PathVisio and CADE, you can also consider the following products
Visio - Simplify and communicate complex information using data-linked diagrams.
LucidChart - LucidChart is the missing link in online productivity suites. LucidChart allows users to create, collaborate on, and publish attractive flowcharts and other diagrams from a web browser.
asciiflow - Infinite ASCII diagrams, save to Google Drive, resize, freeform draw, and export straight to text/html.
draw.io - Online diagramming application
LibreOffice - Draw - Draw, LibreOffice, ODF, open standards, creative software, vector drawing
ASCII Art Maker - A program for creating ASCII graphics from images and text.