After a few years I still use Listary as my main search/launcher. It's very quick, has a very nice look and great system of filters and projects. There are problem with new version to be released, but I'm talking about version number 5.
Keypirinha - A lightning fast and flexible keystroke launcher for Windows. No installation required (portable).
Alfred - Alfred is an award-winning app for macOS which boosts your efficiency with hotkeys, keywords, text expansion and more. Search your Mac and the web, and be more productive with custom actions to control your Mac.
Everything by Voidtools - Everything. Locate files and folders by name instantly. Everything. Small installation file. Clean and simple user interface.
Synapse - Synapse is a semantic launcher written in Vala that you can use to start applications as well as find and access relevant documents and files by making use of the Zeitgeist engine.
ueli - This is a keystroke launcher for Windows and macOS.
Launchy - Launchy is a cross platform app launcher that also launches documents, folders and web browser bookmarks.