What are some alternatives?
When comparing lhorie.github.io mithril and ASP.NET, you can also consider the following products
Vue.js - Reactive Components for Modern Web Interfaces
Ruby on Rails - Ruby on Rails is an open source full-stack web application framework for the Ruby programming...
AngularJS - AngularJS lets you extend HTML vocabulary for your application. The resulting environment is extraordinarily expressive, readable, and quick to develop.
Django - The Web framework for perfectionists with deadlines