Home-Assistant.io - Home Assistant is an open-source home automation platform running on Python 3.
ioBroker - flexible and modular application for the IoT and Smarthome
Domoticz - Domoticz is a lightweight Home Automation System
openHAB - "empowering the smart home" - vendor and technology agnostic open source home automation
Nim Home Assistant (NimHA) - Nim Home Assistant is an open-source home automation platform running on Nim.
Apple HomePod - The new home entertainment system by Apple