Xpadder - Xpadder simulates the keyboard and mouse using your gamepad What does Xpadder let you do?
wjoy - Nintendo wiimote driver for Mac OS X
reWASD - First and only gamepad mapper to make Xbox Elite paddles separate buttons.
Wiiji - Wiiji is the perfect joystick solution for Wii remotes on Mac.
JoyToKey - JoyToKey enables users to control the keyboard using any USB compatible controller (Dualshock 3, Xbox 360, etc.)
Joystick 2 Mouse - Joystick 2 Mouse is a little utility which gives mouse usefulness to associated joysticks and joypads.